In 2018, a young bartender in the Bronx, a coal miner’s daughter in West Virginia, a grieving mother in Nevada and a registered nurse in Missouri join a movement of insurgent candidates challenging powerful incumbents in Congress. Without political experience or corporate money, these four women are attempting to do what many consider impossible.

The biggest tech revolution of the 21st century isn’t digital, it’s biological. A breakthrough called CRISPR gives us unprecedented control over the basic building blocks of life. It opens the door to curing disease, reshaping the biosphere, and designing our own children. This documentary is a provocative exploration of CRISPR’s far-reaching implications, through the eyes of the scientists who discovered it, the families it’s affecting, and the genetic engineers who are testing its limits.